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Douglas L Arnold Selected Research

Relapsing-Remitting Multiple Sclerosis

1/2022Effects of Dimethyl Fumarate on Brain Atrophy in Relapsing-Remitting Multiple Sclerosis: Pooled Analysis Phase 3 DEFINE and CONFIRM Studies.
1/2022Diffusely abnormal white matter converts to T2 lesion volume in the absence of MRI-detectable acute inflammation.
1/2022Comparison of switching to 6-week dosing of natalizumab versus continuing with 4-week dosing in patients with relapsing-remitting multiple sclerosis (NOVA): a randomised, controlled, open-label, phase 3b trial.
1/2022Long-term safety and efficacy of dimethyl fumarate for up to 13 years in patients with relapsing-remitting multiple sclerosis: Final ENDORSE study results.
1/2022Early treatment responses to peginterferon beta-1a are associated with longer-term clinical outcomes in patients with relapsing-remitting multiple sclerosis: Subgroup analyses of ADVANCE and ATTAIN.
9/2021Brain volume change after high-dose immunosuppression and autologous hematopoietic cell transplantation for relapsing-remitting multiple sclerosis.
1/2021Efficacy and safety of alemtuzumab over 6 years: final results of the 4-year CARE-MS extension trial.
11/2020Diroximel fumarate (DRF) in patients with relapsing-remitting multiple sclerosis: Interim safety and efficacy results from the phase 3 EVOLVE-MS-1 study.
10/2020Natalizumab versus fingolimod for patients with active relapsing-remitting multiple sclerosis: results from REVEAL, a prospective, randomised head-to-head study.
8/2020Efficacy and Safety of 2 Fingolimod Doses vs Glatiramer Acetate for the Treatment of Patients With Relapsing-Remitting Multiple Sclerosis: A Randomized Clinical Trial.
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Douglas L Arnold Research Topics

Disease

84Multiple Sclerosis
10/2022 - 02/2005
42Relapsing-Remitting Multiple Sclerosis
01/2022 - 02/2008
15Atrophy
01/2022 - 05/2004
13Infections
01/2021 - 05/2011
11Chronic Progressive Multiple Sclerosis
09/2022 - 01/2017
8Inflammation (Inflammations)
01/2022 - 07/2006
7Disease Progression
01/2022 - 04/2002
7Demyelinating Diseases (Demyelinating Disease)
10/2021 - 01/2006
5Neoplasms (Cancer)
01/2017 - 09/2003
4Headache (Headaches)
01/2019 - 07/2014
3Optic Neuritis (Retrobulbar Neuritis)
05/2022 - 04/2016
3Ganglion Cysts (Ganglion)
05/2022 - 11/2019
3Nasopharyngitis
12/2021 - 04/2016
3Urinary Tract Infections (Urinary Tract Infection)
01/2019 - 07/2014
3Glioma (Gliomas)
11/2009 - 09/2003
2Abdominal Pain (Pain, Abdominal)
12/2021 - 09/2012
2Respiratory Tract Infections (Respiratory Tract Infection)
12/2021 - 01/2017
2Atrioventricular Block
11/2019 - 04/2016
2Human Influenza (Influenza)
01/2019 - 07/2014
2Bradycardia
10/2018 - 01/2018
2Body Weight (Weight, Body)
01/2018 - 09/2016
2Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
11/2012 - 11/2012
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
08/2006 - 03/2003
1Progressive Multifocal Leukoencephalopathy
01/2022
1Pancreatitis
12/2021
1Alopecia (Baldness)
12/2021
1Myelitis
10/2021
1Macular Edema
06/2021
1Opportunistic Infections (Opportunistic Infection)
11/2019
1Bipolar Disorder (Manic Depressive Psychosis)
01/2019
1Hypersensitivity (Allergy)
01/2019
1Herpes Zoster
01/2018
1Supraventricular Tachycardia
01/2018
1Hypertension (High Blood Pressure)
01/2018
1Seizures (Absence Seizure)
01/2018
1Acute Disseminated Encephalomyelitis (Postinfectious Encephalomyelitis)
01/2018
1Leukopenia
01/2018
1Lymphopenia (Lymphocytopenia)
01/2018
1Chickenpox
01/2018
1Neuroinflammatory Diseases
04/2017

Drug/Important Bio-Agent (IBA)

16GadoliniumIBA
01/2022 - 02/2008
14Dimethyl FumarateIBA
01/2022 - 09/2012
12Interferon beta-1aFDA Link
01/2021 - 11/2012
9peginterferon beta-1aIBA
01/2022 - 07/2014
9Glatiramer Acetate (Copaxone)FDA Link
08/2020 - 02/2005
8ozanimodIBA
10/2022 - 04/2016
8Protons (Proton)IBA
11/2009 - 03/2003
7Biomarkers (Surrogate Marker)IBA
11/2021 - 04/2002
6InterferonsIBA
02/2021 - 07/2014
6Alemtuzumab (Campath)FDA Link
01/2021 - 11/2012
6Fingolimod Hydrochloride (FTY720)FDA Link
01/2021 - 01/2018
6ocrelizumabIBA
12/2020 - 01/2017
5Myelin-Oligodendrocyte GlycoproteinIBA
10/2022 - 01/2018
5Sphingosine-1-Phosphate ReceptorsIBA
09/2022 - 04/2016
4siponimodIBA
09/2022 - 01/2018
3Retinaldehyde (Retinal)IBA
05/2022 - 11/2019
3Natalizumab (Tysabri)FDA Link
01/2022 - 01/2018
3FumaratesIBA
01/2022 - 02/2014
3EnzymesIBA
12/2021 - 01/2021
3AntibodiesIBA
01/2020 - 08/2016
3Biological ProductsIBA
01/2020 - 12/2014
3Transaminases (Aminotransferases)IBA
01/2018 - 09/2012
3CreatineIBA
11/2005 - 09/2003
2diroximel fumarateIBA
01/2022 - 11/2020
2Agammaglobulinaemia Tyrosine KinaseIBA
01/2021 - 01/2019
2sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
10/2018 - 04/2016
2amiselimodIBA
10/2018 - 10/2016
2Interferon beta-1b (Betaseron)FDA Link
08/2017 - 08/2016
2Proteins (Proteins, Gene)FDA Link
04/2017 - 07/2006
2Indicators and Reagents (Reagents)IBA
12/2014 - 02/2005
2Pharmaceutical PreparationsIBA
07/2014 - 05/2007
2Monoclonal AntibodiesIBA
11/2012 - 11/2012
2Interferon-betaIBA
11/2012 - 04/2005
2Choline (Choline Chloride)IBA
11/2009 - 09/2003
2N-acetylaspartate (N-acetyl aspartate)IBA
05/2004 - 02/2004
1Immunoglobulin G (IgG)IBA
10/2022
1Cytidine Diphosphate (CDP)IBA
01/2022
1Creatine Kinase (Creatine Phosphokinase)IBA
12/2021
1teriflunomideIBA
12/2021
1AdiponectinIBA
10/2021
1anti-aquaporin 4 autoantibodyIBA
10/2021
1AdipokinesIBA
10/2021
1Protein Isoforms (Isoforms)IBA
10/2021
1ImmunosorbentsIBA
10/2021
1Daclizumab (Zenapax)FDA Link
01/2021
1AutoantibodiesIBA
01/2020
1Acyclovir (Aciclovir)FDA LinkGeneric
10/2019
1evobrutinibIBA
01/2019
1opicinumabIBA
01/2019
1Busulfan (Busulfex)FDA Link
01/2018
1Abatacept (Orencia)FDA Link
04/2017

Therapy/Procedure

26Therapeutics
01/2022 - 04/2002
5Drug Therapy (Chemotherapy)
01/2020 - 10/2008
4Hematopoietic Stem Cell Transplantation
01/2020 - 08/2010
3Cell Transplantation
09/2021 - 02/2015
3Injections
01/2018 - 07/2014
2Stem Cell Transplantation
08/2016 - 02/2008
1Immunomodulation
01/2020
1Retreatment
10/2019
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
03/2017